N-Desmethyl Sildenafil

• Catalog No.: D292200
• CAS Number: 139755-82-1
• M. F.: C21H28N6O4S
• M. W.: 460.54982
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 5-[2-ethoxy-5-(piperazine-1-sulfonyl)phenyl]-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
• IUPAC Traditional name: 5-[2-ethoxy-5-(piperazine-1-sulfonyl)phenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
• Synonyms: UK 103320; 5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one; Desmethylsildenafil

DATABASE IDS

• CAS Number: 139755-82-1

PROPERTIES

• Apperance: White Solid
• Melting Point: 158-160°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Sildenafil, an orally active selective type 5 cGMP phosphodiesterase inhibitor.

REFERENCES

• Walker, D; Xenobiotica, 29, 297 (1999)
• Shim, H., et al.: J. Pharm. Biomed. Anal., 30, 527 (1999)
• Kim, J., et al.: J. Pharm. Biomed. Anal., 32, 317 (1999)
• Pelander, A., et al.: J. Anal. Toxicol., 27, 226 (1999)