6-O-Desmethyl Donepezil β-D-Glucuronide

• Catalog No.: D292018
• CAS Number: 220170-73-0
• M. F.: C29H35NO9
• M. W.: 541.5895

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-({2-[(1-benzylpiperidin-4-yl)methyl]-6-methoxy-3-oxo-2,3-dihydro-1H-inden-5-yl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-({2-[(1-benzylpiperidin-4-yl)methyl]-6-methoxy-3-oxo-1,2-dihydroinden-5-yl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: 6-O-Desmethyl Donepezil Glucuronide; 2,3-Dihydro-6-methoxy-3-oxo-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-5-yl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 220170-73-0

DETAILS

Description (English)

A metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.

REFERENCES

• De Vos, F., et al.: Nuc. Med. Biol., 27, 745 (2000)
• Okereke, C., et al.: Brit. J. Clin. Pharmacol., 58, 41 (2000)