N-Desmethyl Clozapine-d8

• Catalog No.: D292002
• M. F.: C17H17ClN4
• M. W.: 312.79668
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 6-chloro-10-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]-2,9-diazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
• IUPAC Traditional name: 6-chloro-10-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]-2,9-diazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
• Synonyms: 8-Chloro-11-(1-piperazinyl-d8)-5H-dibenzo[B,E][1,4]diazepine

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 102-104°C
• Solubility: Chloroform
• Solubility: Ethanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A major labelled metabolite of clozapine. A potent and selective 5-HT2C serotonin receptor antogonist.

REFERENCES

• Kuoppamaki, M. et al.: Eur. J. Pharm. Mol. Pharm. Sect., 245, 179 (1993)
• Olessen, O.V., et al.: J. Chromatog., 622, 39 (1993)
• Pirmohamed, M., et al.: J. Pharmacol. Exp. Ther., 272, 984 (1995)