N-Desmethyl Dovitinib-d8

• Catalog No.: D291627
• M. F.: C20H19FN6O
• M. W.: 378.4028632

SYNONYMS

• IUPAC name: 4-amino-5-fluoro-3-{6-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]-1H-1,3-benzodiazol-2-yl}-1,2-dihydroquinolin-2-one
• IUPAC Traditional name: 4-amino-5-fluoro-3-{5-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]-3H-1,3-benzodiazol-2-yl}-1H-quinolin-2-one
• Synonyms: 4-Amino-5-fluoro-3-[6-(1-piperazinyl-d8)-1H-benzimidazol-2-yl]-2(1H)-quinolinone

DETAILS

Description (English)

Labelled Dovitinib (D537000 )derivative; a benzimidazole quinolinone for inhibiting a checkpoint kinase 1 and its use in combination therapy for cancer.

REFERENCES

• Bosserhoff, A., et al.: J. Investigative Dermat., 114, 395 (2000)
• Anon., et al.: Eur. J. Cancer, 3 (suppl. 2), 148 (2000)