N-Desmethyl Diltiazem-d3 Hydrochloride

• Catalog No.: D291612
• M. F.: C21H25ClN2O4S
• M. W.: 436.9522
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (2S,3S)-2-(4-methoxyphenyl)-5-{2-[(^2H₃)methylamino]ethyl}-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride
• IUPAC Traditional name: (2S,3S)-2-(4-methoxyphenyl)-5-{2-[(^2H₃)methylamino]ethyl}-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl acetate hydrochloride
• Synonyms: N-Monodesmethyldiltiazem-d3; N-Demethyldiltiazem-d3; (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino-d4)ethyl]-1,5-benzothiazepin-4(5H)-one-d3 Monohydrochloride

PROPERTIES

• Apperance: White Solid
• Melting Point: 186-188°C
• Solubility: Chloroform
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Diltiazem (D460620), an antianginal, antihypertensive pharmaceutical. Diltiazem regulates Calcium release from intracellular stores in neutrophils.

REFERENCES

• Li, R., et al.: J. Med. Chem., 35, 3246 (1992)