O-Desmethyl Diltiazem Hydrochloride

• Catalog No.: D291605
• CAS Number: 142926-07-6
• M. F.: C21H25ClN2O4S
• M. W.: 436.9522
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-hydroxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride
• IUPAC Traditional name: (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl acetate hydrochloride
• Synonyms: (2S,3S)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride; (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride

DATABASE IDS

• CAS Number: 142926-07-6

PROPERTIES

• Apperance: White Solid
• Melting Point: 218-224°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Diltiazem (D460620), an antianginal, antihypertensive pharmaceutical.

REFERENCES

• Li, R., et al.: J. Med. Chem., 35, 3246 (1992)