(R)-Desmethyl Citalopram Hydrochloride

• Catalog No.: D291565
• CAS Number: 144010-85-5
• M. F.: C19H20ClFN2O
• M. W.: 346.8263032
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1R)-1-(4-fluorophenyl)-1-[3-(methylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile hydrochloride
• IUPAC Traditional name: (1R)-1-(4-fluorophenyl)-1-[3-(methylamino)propyl]-3H-2-benzofuran-5-carbonitrile hydrochloride
• Synonyms: (R)-(-)-N-Demethylcitalopram Hydrochloride; (1R)-1-(4-Fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-5-isobenzofurancarbonitrile Hydrochloride

DATABASE IDS

• CAS Number: 144010-85-5

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 70-72°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

The (R)-enantiomer metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant.

REFERENCES

• Yue, Q., et al.: Br. J. Clin. Pharm., 28, 639 (1989)
• Milne, R., et al.: Drugs, 41, 450 (1989)
• Personne, M., et al.: J. Toxicol. Clin. Toxicol., 35, 237 (1989)
• Olesen, O., et al.: Pharmacology, 59, 298 (1989)
• Zheng, Z., et al.: Ther. Drug Monit., 22, 2