(S)-(-)-O-Desmethyl Carvedilol_Molecular_structure_CAS_123372-13-4)

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(S)-(-)-O-Desmethyl Carvedilol
Catalog No.	D291485	Name	Toronto Research Chemicals
CAS Number	123372-13-4	Website	http://www.trc-canada.com
M. F.	C23H24N2O4	Telephone	+1 (416) 665-9696
M. W.	392.44766	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage	-20°C Freezer	Chembase ID: 166411

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SYNONYMS

IUPAC name

2-(2-{[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino}ethoxy)phenol

IUPAC Traditional name

2-(2-{[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino}ethoxy)phenol

Synonyms

(S)-(-)-O-Desmethylcarvedilol

(S)- 2-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]phenol

DATABASE IDS

CAS Number

123372-13-4

PROPERTIES

Certificate of Analysis	Download
Apperance	Off-White Solid
Melting Point	155-156°C
Solubility	Chloroform
Solubility	Hot Methanol
Solubility	Tetrahydrofuran
MSDS Link	Download
Storage Condition	-20°C Freezer

DETAILS

Description (English)

An optically active metabolite of Carvedilol (C184625), a nonselective β-adrenergic blocker with α1-blocking activity. [α]D= -18.7 (c= 0.1 methanol)

REFERENCES

Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987)
Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1987)
Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1987)
Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (1987)