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O-Desmethyl Astemizole_Molecular_structure_CAS_73736-50-2)
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O-Desmethyl Astemizole

Catalog No. D290750 Name Toronto Research Chemicals
CAS Number 73736-50-2 Website http://www.trc-canada.com
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Storage Refrigerator Chembase ID: 166385

SYNONYMS

IUPAC name
4-{2-[4-({1-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazol-2-yl}amino)piperidin-1-yl]ethyl}phenol
IUPAC Traditional name
4-{2-[4-({1-[(4-fluorophenyl)methyl]-1,3-benzodiazol-2-yl}amino)piperidin-1-yl]ethyl}phenol
Synonyms
O-Demethylastemizole
4-[2-[4-[[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]-1-piperidinyl]ethyl]phenol
R 44271
Desmethylastemizole

DATABASE IDS

CAS Number 73736-50-2

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 92-94°C
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
A metabolite of Astemizole.

REFERENCES

  • Nagata, K., et al.: J. Biol. Chem., 268, 24720 (1993)
  • Benton, R., et al.: Clin. Pharmacol. Ther., 59, 383 (1993)
  • Hashizume, T., et al.: Drug Metab. Dispos., 26, 566 (1993)
  • Scarborough, P., et al.: Drug Metab. Rev., 31, 205 (1993)