Desloratadine-d4

• Catalog No.: D290252
• CAS Number: 381727-29-3
• M. F.: C19H19ClN2
• M. W.: 310.82056
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 13-chloro-2-[(2,2,6,6-^2H₄)piperidin-4-ylidene]-4-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaene
• IUPAC Traditional name: 13-chloro-2-[(2,2,6,6-^2H₄)piperidin-4-ylidene]-4-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaene
• Synonyms: Azomyr-d4; Descarboethoxyloratadine-d4; NSC 675447-d4; Neoclarityn-d4; 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-d4; Aerius-d4; Allex-d4; Clarinex-d4; Opulis-d4; Sch 34117-d4

DATABASE IDS

• CAS Number: 381727-29-3

PROPERTIES

• Apperance: Pale Yellow to Light Beige Solid
• Melting Point: 150-151°C
• Solubility: Hexane
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Labelled Desloratadine (D290250). Nonsedating-type labelled histamine H1-receptor antagonist. An active labelled metabolite of Loratadine. Also inhibits generation and release of inflammatory mediators from basophils and mast cells.

REFERENCES

• Kreutner, W., et al.: Arzneimittel-Forsch., 50, 345 (2000)
• Salmun, L.M., et al.: Clin. Ther., 22, 613 (2000)
• Agrawal, D.K., et al.: Expert Opin. Invest. Drugs, 10, 547 (2000)