Des(isopropylthiazolyl) Hydantoin Ritonavir

• Catalog No.: D290215
• CAS Number: 1010809-61-6
• M. F.: C29H34N4O5S
• M. W.: 550.66906

SYNONYMS

• IUPAC name: 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-5-[(4R)-2,5-dioxo-4-(propan-2-yl)imidazolidin-1-yl]-3-hydroxy-1,6-diphenylhexan-2-yl]carbamate
• IUPAC Traditional name: 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(4R)-4-isopropyl-2,5-dioxoimidazolidin-1-yl]-1,6-diphenylhexan-2-yl]carbamate
• Synonyms: N-[(1S,2S,4S)-2-Hydroxy-4-[(4S)-4-(1-methylethyl)-2,5-dioxo-1-imidazolidinyl]-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester; Thiazol-5-ylmethyl (2S,3S,5S)-3-hydroxy-5-[(S)-4-isorpopyl-2,5-dioxoimidazolidin-1-yl]-1,6-diphenylhexan-2-ylcarbamate; 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-1-benzyl-2-hydroxy-4-((4S)-4-isopropyl-2,5-dioxoimidazolidin-1-yl)-5-phenylpentyl]carbamate

DATABASE IDS

• CAS Number: 1010809-61-6

DETAILS

Description (English)

Ritonavir (R535000) derivative with potential use in the treatment of viral infections. Cytochrome P450 oxidase inhibitor.

REFERENCES

• Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994)
• Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (1994)