N-Deshydroxyethyl Dasatinib-d8

• Catalog No.: D290002
• M. F.: C20H22ClN7OS
• M. W.: 443.95298
• Storage: Refrigerator

SYNONYMS

• IUPAC name: N-(2-chloro-6-methylphenyl)-2-({2-methyl-6-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]pyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
• IUPAC Traditional name: N-(2-chloro-6-methylphenyl)-2-({2-methyl-6-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]pyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
• Synonyms: N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl-d8)-4-pyrimidinyl]amino]-5-thiazolecarboxamide; Dasatinib Metabolite M4-d8

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >280°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

A labelled metabolite of Dasatinib. Used in the treatment of cancers and immune diseases.

REFERENCES

• Trentham, D., et al.: Biochem. J., 126, 635 (1972)
• Matsuguchi, T., et al.: J. Biol. Chem., 269, 5016 (1972)
• Berman, E., et al.: Leukemia Res., 24, 289 (1972)
• Tokarski, J., et al.: Cancer Res., 2006, 66, 5790 (1972)