4-Desmethoxy-4-bromo Trimethoprim-d3

• Catalog No.: D290312
• M. F.: C13H15BrN4O2
• M. W.: 339.1878

SYNONYMS

• IUPAC name: 5-{[3-bromo-4-(^2H₃)methoxy-5-methoxyphenyl]methyl}pyrimidine-2,4-diamine
• IUPAC Traditional name: 5-{[3-bromo-4-(^2H₃)methoxy-5-methoxyphenyl]methyl}pyrimidine-2,4-diamine
• Synonyms: 2,4-Diamino-5-[3-bromo-4-(methoxy-d3)-5-methoxybenzyl]pyrimidine; 2,4-Diamino-5-(5-bromoveratryl)pyrimidine; 5-[3’-Bromo-4’-(methoxy-d3)-5’-methoxybenzyl]-2,4-diaminopyrimidine; 2,4-Diamino-5-[3-methoxy-4-(methoxy-d3)-5-bromobenzyl]pyrimidine; 5-[[3-Bromo-4-(methoxy-d3)-5-methoxyphenyl]methyl]-2,4-diaminopyrimidine

DETAILS

Description (English)

A labelled impurity of Trimethoprim (T795615) with inhibitory effects on the enzyme dihydrofolate reductase.

REFERENCES

• Kompis, I. et al.: Enzyme Inhib. Proc. Meet., 177 (1980)
• Hess, S. et al.: J. Pharmac. Biomed. Anal., 25, 531 (1980)