Desethyl Sildenafil

• Catalog No.: D289600
• CAS Number: 139755-91-2
• M. F.: C20H26N6O4S
• M. W.: 446.52324
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 5-{2-hydroxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
• IUPAC Traditional name: 5-[2-hydroxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
• Synonyms: 5-[2-Hydroxy-5-(4-methylpiperazinylsulphonyl)phenyl]1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyramidin-7-one; 5-[2-Hydroxy-5-[[4-(methyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one

DATABASE IDS

• CAS Number: 139755-91-2

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 279-281°C (dec.)
• Solubility: Aqueous Base
• Solubility: DMSO (Sparingly)
• Storage Condition: Refrigerator

DETAILS

Description (English)

A metabolite of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.

REFERENCES

• Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996)
• Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)