7-Descarbamoyl 17-Amino Geldanamycin-15N

• Catalog No.: D288837
• M. F.: C27H38N2O7
• M. W.: 503.5932289

SYNONYMS

• IUPAC name: (4E,6Z,8R,9S,10E,12S,13R,14R,16R)-19-amino-9,13-dihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaene-3,20,22-trione
• IUPAC Traditional name: (4E,6Z,8R,9S,10E,12S,13R,14R,16R)-19-amino-9,13-dihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaene-3,20,22-trione
• Synonyms: 17-Amino-7-decarbamoyl Geldanamycin-15N; 17-Amino-7-O-de(aminocarbonyl)-17-demethoxy-geldanamycin-15N

PROPERTIES

• Apperance: Purple Solid
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate

DETAILS

Description (English)

An intermediate in the preparation of labelled 17-(Allylamino)geldanamycin (17AAG) metabolites

REFERENCES

• Schnur, R., et al.: J. Med. Chem., 38, 3813 (1995)
• Rastelli, G., et al.: Bioorg. Med. Chem. Lett., 15, 5016 (1995)