N-Desethyl Acetildenafil-d8 Dihydrochloride

• Catalog No.: D288822
• M. F.: C23H30N6O3
• M. W.: 438.5227
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 5-(2-ethoxy-5-{2-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]acetyl}phenyl)-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
• IUPAC Traditional name: 5-(2-ethoxy-5-{2-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]acetyl}phenyl)-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
• Synonyms: 5-[2-Ethoxy-5-(1-piperazinyl-d8-acetyl)phenyl]-1,4-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one Dihydrochloride

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 196-199°C
• Solubility: DMSO
• Solubility: Methanol (hot)
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A labelled pyrazolopyrimidinone derivative as cGMP phosphodiesterase inhibitor.

REFERENCES

• Hucker, H., et al.: Drug Metab. Dispos., 1, 721 (1973)
• Tulshian, D., et al.: J. Med. Chem., 36, 1210 (1973)
• Brogden, R., et al.: Drugs, 16, 97 (1973)
• Korinek, V., et al.: Science, 275, 1784 (1973)
• Blaya, C., et al.: Eur. J. Pharmacol., 354, 99 (1998