N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride

• Catalog No.: D288740
• CAS Number: 111974-74-4
• M. F.: C17H17N3S
• M. W.: 295.40198
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 10-(piperazin-1-yl)-2-thia-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
• IUPAC Traditional name: 10-(piperazin-1-yl)-2-thia-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
• Synonyms: 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine, Dihydrochloride, DBTP,

DATABASE IDS

• CAS Number: 111974-74-4

PROPERTIES

• Apperance: Off-White to Pale-Yellow Solid
• Melting Point: 287-292°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.

REFERENCES

• DeVane, C., et al.: Clin. Pharmacokinet., 40, 509 (2001)
• Lin, S., et al.: J. Anal. Toxicol., 28, 443 (2001)
• Zhou, S., et al.: Curr. Drug Metab., 5, 415 (2001)
• Grimm, S., et al.: Br. J. Clin. Pharmacol., 61, 58 (2001)