4-Desacetyl Vinblastine Discontinued. See D288440

• Catalog No.: D288728
• CAS Number: 3352-69-0
• M. F.: C44H56N4O8
• M. W.: 768.93744

SYNONYMS

• IUPAC name: methyl (9R,10S,11R,12R,19R)-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• IUPAC Traditional name: methyl (9R,10S,11R,12R,19R)-12-ethyl-4-[(1R,13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• Synonyms: O4-Desacetylvinblastine; Deacetylvinblastine; O4-Deacetylvincaleukoblastine; 4-Deacetylvinblastine

DATABASE IDS

• CAS Number: 3352-69-0

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 189-191°C
• Solubility: Dichloromethane
• Solubility: Methanol

DETAILS

Description (English)

A pro-drug of Vinblastine. Antitumor agent used for treatment of prostate cancer.

REFERENCES

• Raghavan, D., et al.: Eur. J. Cancer, 33, 566 (1997)
• Brady, S.F., et al.: J. Med. Chem., 45, 4706 (1997)