21-Desacetyl Deflazacort-d3 (Major)

• Catalog No.: D288697
• M. F.: C23H29NO5
• M. W.: 399.48006
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,9,13-trimethyl(10,10,11-^2H₃)-5-oxa-7-azapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icosa-6,14,17-trien-16-one
• IUPAC Traditional name: (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,9,13-trimethyl(10,10,11-^2H₃)-5-oxa-7-azapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icosa-6,14,17-trien-16-one
• Synonyms: (11β,16β)-11,21-Dihydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-di-one-d3; L 6485-d3; Deacetyldeflazacort-d3; Deflazacortalcohol-d5

PROPERTIES

• Apperance: White Solid
• Melting Point: 208-210°C (dec.)
• Solubility: Chloroform
• Solubility: Ethyl Acetate
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

A labelled metabolite of Deflazacort (D228975), a systemic corticosteroid, a derivative of Prednisolone and used for rheumatoid arthritis and lupus.

REFERENCES

• Hahn, T.J., et al.: Calcif. Tissue Int., 31, 109 (1980)
• Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984)