4'-Deoxy Vincristine

• Catalog No.: D288330
• CAS Number: 68135-16-0
• M. F.: C46H56N4O9
• M. W.: 808.95824

SYNONYMS

• IUPAC name: methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15R,17R)-17-ethyl-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• IUPAC Traditional name: methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(1R,13S,15R,17R)-17-ethyl-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• Synonyms: 4'-Deoxyleurocristine; 4'-Deoxy-22-oxo-vincaleukoblastine

DATABASE IDS

• CAS Number: 68135-16-0

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 186-188°C
• Solubility: Chloroform
• Solubility: Methanol

DETAILS

Description (English)

A Vincristine derivative as neoplasm inhibitor.

REFERENCES

• Borman, L.J., et al.: Biol. Chem., 263, 6945 (1988)
• Borman, L., et al.: Biochem. Pharmacol., 38, 715 (1988)
• Arap, W., et al.: Science, 279, 377 (1988)