5'-Deoxy-5'-(methylthio)adenosine_Molecular_structure_CAS_2457-80-9)

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5'-Deoxy-5'-(methylthio)adenosine
Catalog No.	D242600	Name	Toronto Research Chemicals
CAS Number	2457-80-9	Website	http://www.trc-canada.com
M. F.	C11H15N5O3S	Telephone	+1 (416) 665-9696
M. W.	297.3335	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 134202

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SYNONYMS

IUPAC name

(2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methylsulfanyl)methyl]oxolane-3,4-diol

IUPAC Traditional name

methylthioadenosine

Synonyms

5'-Deoxy(methylthio)adenosine

5'-(Methylthio)-5'-deoxyadenosine

1-(6-Amino-9H-purin-9-yl)-1-deoxy-5-S-methyl-5-thio-β-D-ribofuranose

5'-(Methylthio)adenosine

NSC 335422

5'-S-Methylthioadenosine

Vitamin L2

5'-S-Methyl-5'-thioadenosine

DATABASE IDS

CAS Number

2457-80-9

PROPERTIES

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DETAILS

Description (English)

5′-Deoxy-5′-(methylthio)adenosine (Methylthioadenosine) may be used as a substrate to study the specificity and kinetics of 5′-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethi

REFERENCES

Pegg, A., et al.: Biochem. J., 115, 241 (1969)
Olopade, O., et al.: Cancer Res., 53, 2410 (1969)
Hartmann, S., et al.: Clin. Chem., 52, 1127 (1969)
Penner, N., et al.: J. Pharm. Biomed. Anal., 52, 534 (1969)