N2-(Deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline

• Catalog No.: D239615
• CAS Number: 142038-31-1
• M. F.: C21H22N10O4
• M. W.: 478.46398
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 2-amino-8-({1,6-dimethyl-1H-imidazo[4,5-g]quinoxalin-2-yl}amino)-9-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
• IUPAC Traditional name: 2-amino-8-({1,6-dimethylimidazo[4,5-g]quinoxalin-2-yl}amino)-9-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
• Synonyms: 2'-Deoxy-8-[(3,8-dimethyl-3H-imidazo[4,5-f]quinoxalin-2-yl)amino]guanosine; dG-C8-MeIQx

DATABASE IDS

• CAS Number: 142038-31-1

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 220°C (dec.)
• Solubility: DMSO
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

MeIQx-DNA adducts exist in human tissues and this adduct formation may be involved in human cancer development.

REFERENCES

• Ohshima, H., et al.: Mutat. Res., 305, 253 (1994)
• Pais, P., et al.: J. Agric. Food Chem., 47, 1098 (1994)
• Lakshmi, V., et al.: Chem. Res. Toxicol., 18, 1038 (1994)