2'-Deoxy-3',5'-di-O-benzoyl-2',2'-difluorocytidine-13C,15N2

• Catalog No.: D232667
• M. F.: C23H19F2N3O6
• M. W.: 474.38973903

SYNONYMS

• IUPAC name: (2R,3R)-5-[4-amino-2-oxo-1,2-dihydro(2-^1^3C,1,3-^1^5N₂)pyrimidin-1-yl]-2-[(benzoyloxy)methyl]-4,4-difluorooxolan-3-yl benzoate
• IUPAC Traditional name: (2R,3R)-5-[4-amino-2-oxo(2-^1^3C,1,3-^1^5N₂)pyrimidin-1-yl]-2-[(benzoyloxy)methyl]-4,4-difluorooxolan-3-yl benzoate
• Synonyms: 2’-Deoxy-2’,2’-difluoro-3’,5’-bis-O-benzoylcytidine-13C,15N2

PROPERTIES

• Apperance: Tan Solid
• Solubility: DMSO
• Solubility: Ethyl Acetate (Hot)

DETAILS

Description (English)

A labelled (β-anomer) intermediate of Gemcitabine; antitumor compound.

REFERENCES

• Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990)
• Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1990)
• Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1990)