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2'-Deoxy-3',5'-di-O-benzoyl-2',2'-difluorocytidine_Molecular_structure_CAS_134790-39-9)
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2'-Deoxy-3',5'-di-O-benzoyl-2',2'-difluorocytidine

Catalog No. D232665 Name Toronto Research Chemicals
CAS Number 134790-39-9 Website http://www.trc-canada.com
M. F. C23H19F2N3O6 Telephone +1 (416) 665-9696
M. W. 471.4102664 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 165892

SYNONYMS

IUPAC name
[(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-(benzoyloxy)-4,4-difluorooxolan-2-yl]methyl benzoate
IUPAC Traditional name
[(2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-(benzoyloxy)-4,4-difluorooxolan-2-yl]methyl benzoate
Synonyms
2’-Deoxy-2’,2’-difluoro-3’,5’-bis-O-benzoylcytidine

DATABASE IDS

CAS Number 134790-39-9

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 229-232°C
Solubility DMSO
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
A (β-anomer) intermediate of Gemcitabine; antitumor compound.

REFERENCES

  • Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990)
  • Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1990)
  • Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1990)