11-Deoxy Cortisol-d7 (Major)

• Catalog No.: D232602
• M. F.: C21H30O4
• M. W.: 346.4605
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (1S,2R,10R,11S,14R,15S)-14-hydroxy-14-[2-hydroxy(^2H₂)acetyl]-2,15-dimethyl(4,4,6,8,8-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC Traditional name: (1S,2R,10R,11S,14R,15S)-14-hydroxy-14-[2-hydroxy(^2H₂)acetyl]-2,15-dimethyl(4,4,6,8,8-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• Synonyms: 17,21-Dihydroxypregn-4-en-3,20-dione-d7; SKF 3050-d7; 4-Pregnene-17α,21-diol-3,20-dione-d7; Cortifen-d7; 11-Deoxy-17-hydroxycorticosterone-d7; Cortexolone-d7; NSC 18317-d7; Reichstein S-d7; Reichstein's Compound S-d7

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 187-194°C
• Solubility: Chloroform
• Solubility: Dioxane
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Glucocorticoid receptor binding.A representative lots showed approximately 10% d8.

REFERENCES

• Gazdar, A., et al.: Cancer Res., 50, 5488, (1990)
• Bird, I., et al.: Endocrinology, 134, 2468 (1990)
• Auchus, R., et al.: J. Biol. Chem., 273, 3158 (1990)
• Dardis, A., et al.: J. Endocrinol., 179, 131 (1990)