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Desacetyl Acetaminophen Glutathione_Molecular_structure_CAS_129762-76-1)
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Desacetyl Acetaminophen Glutathione

Catalog No. D288400 Name Toronto Research Chemicals
CAS Number 129762-76-1 Website http://www.trc-canada.com
M. F. C16H22N4O7S Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
(2S)-2-amino-4-{[(1R)-2-[(5-amino-2-hydroxyphenyl)sulfanyl]-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid
IUPAC Traditional name
(2S)-2-amino-4-{[(1R)-2-[(5-amino-2-hydroxyphenyl)sulfanyl]-1-(carboxymethylcarbamoyl)ethyl]carbamoyl}butanoic acid
Synonyms
N-[S-(5-Amino-2-hydroxyphenyl)-N-L-γ-glutamyl-L-cysteinyl]glycine

DATABASE IDS

CAS Number 129762-76-1

PROPERTIES

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DETAILS

Description (English)
The hepatic metabolite of p-Aminophenol. The aminophenol glutathione S-conjugates formed induce p-Aminophenol nephrotoxicity by a pathway dependent on γ-glutamyl transpeptidase.

REFERENCES

  • Eckert, K.G., et al.: Xenobiotica, 20, 333 (1990)
  • Klos, C., et al.: Toxicol. Applied Pharmacol., 115, 98 (1990)