3-Desacetyl Cefotaxime Lactone

• Catalog No.: D288390
• CAS Number: 66340-33-8
• M. F.: C14H13N5O5S2
• M. W.: 395.41352

SYNONYMS

• IUPAC name: (2Z)-2-(2-amino-1,3-thiazol-4-yl)-N-[(4R,5R)-3,11-dioxo-10-oxa-6-thia-2-azatricyclo[6.3.0.0^2,^5]undec-1(8)-en-4-yl]-2-(methoxyimino)acetamide
• IUPAC Traditional name: (2Z)-2-(2-amino-1,3-thiazol-4-yl)-N-[(4R,5R)-3,11-dioxo-10-oxa-6-thia-2-azatricyclo[6.3.0.0^2,^5]undec-1(8)-en-4-yl]-2-(methoxyimino)acetamide
• Synonyms: [5aR-[5aα,6β(Z)]]-2-Amino-α-(methoxyimino)-N-(1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl)-4-thiazoleacetamide

DATABASE IDS

• CAS Number: 66340-33-8

DETAILS

Description (English)

3-Desacetyl Cefotaxime Lactone is an impurity of Cefotaxime sodium (C242950). 3-Desacetyl Cefotaxime Lactone is also a degradation product for other cephalosporin antibiotics such as: Ceftriaxone (C245000), Cefodizime and Ceftiofur (C244700).

REFERENCES

• Amaker, R., et al.: Antimicrob. Agents Chemother., 40, 1139 (1996)
• Taylor, P., et al.: Clin. Biochem., 38, 328 (1996)