3-Demethyl Thiocolchicine 3-O-β-D-Glucuronide

• Catalog No.: D231335
• CAS Number: 819802-34-1
• M. F.: C27H31NO11S
• M. W.: 577.60014
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2R,3R,4R,5S,6R)-6-{[(10S)-10-acetamido-3,4-dimethoxy-14-(methylsulfanyl)-13-oxotricyclo[9.5.0.0^2,^7]hexadeca-1(16),2(7),3,5,11,14-hexaen-5-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2R,3R,4R,5S,6R)-6-{[(10S)-10-acetamido-3,4-dimethoxy-14-(methylsulfanyl)-13-oxotricyclo[9.5.0.0^2,^7]hexadeca-1(16),2(7),3,5,11,14-hexaen-5-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: (7S)-7-(Acetylamino)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-3-yl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 819802-34-1

PROPERTIES

• Apperance: Yellow SOlid
• Melting Point: >234°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

The major metabolite of Thiocolchicoside (TCC), a muscle relaxant drug.

REFERENCES

• Sandouk, P., et al.: Biopharm. Drug Dispos., 15, 87 (1994)
• Perucca, E., et al.: Eur. J. Drug Metab. Pharmacokinet., 20, 301 (1994)
• Advokat, C., et al.: Pharmacol. Biochem. Behav., 63, 527 (1994)