N-Demethyl Roxithromycin

• Catalog No.: D231265
• CAS Number: 118267-18-8
• M. F.: C40H74N2O15
• M. W.: 823.01996
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-6-{[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-10-(2,4,7-trioxa-1-azaoctan-1-ylidene)-1-oxacyclotetradecan-2-one
• IUPAC Traditional name: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-6-{[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-10-(2,4,7-trioxa-1-azaoctan-1-ylidene)-1-oxacyclotetradecan-2-one
• Synonyms: N-Demethylroxithromycin; (9E)-9-[O-[(2-Methoxyethoxy)methyl]oxime]-N-demethyl Erythromycin; RU 44981; (E)-N-Demethylroxithromycin

DATABASE IDS

• CAS Number: 118267-18-8

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 96-98°C
• Solubility: Chloroform
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Roxithromycin (R700850).

REFERENCES

• Lindstrom, T., et al.: Antimicrob. Agents Chemother., 37, 265 (1993)
• Shimada, T., et al.: J. Pharmacol. Exp. Ther., 270, 414 (1993)
• Yamazaki, H., et al.: J. Toxicol. Sci., 21, 215 (1993)