N-Demethyl Rifampin-d8

• Catalog No.: D231252
• M. F.: C42H56N4O12
• M. W.: 808.91364

SYNONYMS

• IUPAC name: (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-26-[(E)-N-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]carboximidoyl]-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate
• IUPAC Traditional name: (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-26-[(E)-N-[(2,2,3,3,5,5,6,6-^2H₈)piperazin-1-yl]carboximidoyl]-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate
• Synonyms: Rifampicin AF/AP-d8; Demethylrifampicin-d8; N-Demethylrifampicin-d8; 3-[(1-Piperazinylimino-d8)methyl]rifamycin; 4-N-Demethylrifampicin-d8; 3-(Piperazino-d8)iminomethyl Rifamycin SV; AF/AP-d8; N-Demethylrifampin-d8; NSC 143416-d8

DETAILS

Description (English)

Labelled N-Demethyl Rifampin (D231250). N-Demethyl Rifampin is a metabolite of Rifampicin (R508000).

REFERENCES

• Marsili, L., et al.: J. Antibiot., 37, 1209 (1984)
• Nikaido, H., et al.: Antimicrob. Ag. Chemother., 37, 1393 (1984)
• Piddock, L., et al.: J. Antimicrob. Chemother., 45, 159 (1984)