7-O-Demethyl Rapamycin

• Catalog No.: D231240
• CAS Number: 151519-50-5
• M. F.: C50H77NO13
• M. W.: 900.14528
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18,30-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0^4,^9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
• IUPAC Traditional name: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18,30-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0^4,^9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
• Synonyms: 7-O-Demethyl Cypher; 7-O-Demethyl Sirolimus; 7-O-Demethyl Rapammune

DATABASE IDS

• CAS Number: 151519-50-5

PROPERTIES

• Apperance: White Solid
• Melting Point: 133-138°C
• Solubility: Chloroform
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Rapamycin metabolite.

REFERENCES

• Dickman, D., et al.: Bioorg. Med. Chem. Lett., 10, 1405 (2000)
• Davis, D., et al.: Clin. Biochem., 33, 31 (2000)
• Cummins, C., et al.: J. Pharmacol. Exper. Ther., 308, 143 (2000)
• Scholer, A., et al.: Clin. Lab., 52, 325 (2000)