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3-Demethyl Colchicine

Catalog No. D230885 Name Toronto Research Chemicals
CAS Number 7336-33-6 Website http://www.trc-canada.com
M. F. C21H23NO6 Telephone +1 (416) 665-9696
M. W. 385.41042 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 165747

SYNONYMS

IUPAC name
N-[(10S)-5-hydroxy-3,4,14-trimethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl]acetamide
IUPAC Traditional name
N-[(10S)-5-hydroxy-3,4,14-trimethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl]acetamide
Synonyms
O3-Demethylcolchicine
3-Demethylcolchicine
N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-acetamide
3-Demethyl-(-)-colchicine
3-Desmethylcolchicine

DATABASE IDS

CAS Number 7336-33-6

PROPERTIES

Certificate of Analysis Download
Apperance Yellow Solid
Melting Point 163-166°C
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
A metabolite of Colchicine (C640000). Has shown anti-tumor activity.

REFERENCES

  • Martinez, M., et al.: J. Appl. Toxicol., 15, 49 (1995)
  • De Vincenzo, R., et al.: Oncol. Res., 11, 145(1995)
  • Das, D., et al.: Biochim. Biophys. Acta., 1502, 351 (1995)
  • Wagner, B., et al.: J. Biol. Chem., 275, 22461(1995)