2-Demethyl Colchicine

• Catalog No.: D230880
• CAS Number: 102491-80-5
• M. F.: C21H23NO6
• M. W.: 385.41042
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: N-[(10S)-4-hydroxy-3,5,14-trimethoxy-13-oxotricyclo[9.5.0.0^2,^7]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl]acetamide
• IUPAC Traditional name: N-[(10S)-4-hydroxy-3,5,14-trimethoxy-13-oxotricyclo[9.5.0.0^2,^7]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl]acetamide
• Synonyms: O2-Demethylcolchicine; N-[(7S)-5,6,7,9-Tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; (-)-2-Demethylcolchicine; NSC 180533

DATABASE IDS

• CAS Number: 102491-80-5

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 166-168°C
• Solubility: Chloroform (Sparingly)
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Colchicine (C640000). Has shown anti-tumor activity.

REFERENCES

• Martinez, M., et al.: J. Appl. Toxicol., 15, 49 (1995)
• De Vincenzo, R., et al.: Oncol. Res., 11, 145(1995)
• Das, D., et al.: Biochim. Biophys. Acta., 1502, 351 (1995)
• Wagner, B., et al.: J. Biol. Chem., 275, 22461(1995)