rac Demethyl Citalopram-d3 Hydrochloride

• Catalog No.: D230848
• M. F.: C19H20ClFN2O
• M. W.: 346.8263032
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 1-(4-fluorophenyl)-1-{3-[(^2H₃)methylamino]propyl}-1,3-dihydro-2-benzofuran-5-carbonitrile hydrochloride
• IUPAC Traditional name: 1-(4-fluorophenyl)-1-{3-[(^2H₃)methylamino]propyl}-3H-2-benzofuran-5-carbonitrile hydrochloride
• Synonyms: 1-(4-Fluoro-phenyl)-1-[3-(methyl-d3)amino-propyl]-1,3-dihydro-isobenzofuran-5-carbonitrile Hydrochloride; 1-[3-(Methylamino-d3)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 78-80°C
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A labelled metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant.

REFERENCES

• Gnerre, C., et al.: J. Pharm. Pharmacol., 53, 1125 (2001)
• Hagg, S., et al.: Br. J. Clin. Pharmacol., 51, 169 ( 2001), von Moltke, L., et al.: Drug Metab. Dispos., 29, 1102 (2001)
• Reis, M., et al.: Ther. Drug Monit., 27, 469 (2001)