Demeclocycline-d6 HydrochlorideDiscontinued

• Catalog No.: D230727
• M. F.: C21H22Cl2N2O8
• M. W.: 501.31398

SYNONYMS

• IUPAC name: (4S,4aS,5aS,6S,12aS)-4-[bis(^2H₃)methylamino]-7-chloro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
• IUPAC Traditional name: (4S,4aS,5aS,6S,12aS)-4-[bis(^2H₃)methylamino]-7-chloro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide hydrochloride
• Synonyms: Ledermycin-d6 Hydrochloride; [4S-(4α,4aα,5aα,6β,12aα)]-7-Chloro-4-(dimethyl-d6)amino-d3-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride; Meciclin-d6; Detravis-d6; 6-Demethyl-7-chlorotetracycline-d6 Hydrochloride; Demetraciclina-d6

DETAILS

Description (English)

Labelled Demeclocycline (D230725). An antibiotic related to tetracycline and produced by streptomyces aureofaciens. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.

REFERENCES

• Jilka, R., et al.: J. Clin. Invest., 104, 439 (1999)
• Hauge, E; Bone, 28, 556 (1999)
• Dobnig, H., et al.: J. Clin. Endocrinol. Metab., 90, 3970 (1999)