Demeclocycline Hydrochloride

• Catalog No.: D230725
• CAS Number: 64-73-3
• M. F.: C21H22Cl2N2O8
• M. W.: 501.31398
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
• IUPAC Traditional name: demeclocycline hydrochloride
• Synonyms: 6-Demethyl-7-chlorotetracycline Hydrochloride; Demetraciclina; Meciclin; Detravis; [4S-(4α,4aα,5aα,6β,12aα)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride; Ledermycin Hydrochloride

DATABASE IDS

• CAS Number: 64-73-3

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: >225°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

An antibiotic related to tetracycline and produced by streptomyces aureofaciens. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.

REFERENCES

• Jilka, R., et al.: J. Clin. Invest., 104, 439 (1999)
• Hauge, E; Bone, 28, 556 (1999)
• Dobnig, H., et al.: J. Clin. Endocrinol. Metab., 90, 3970 (1999)