11-Dehydro Thromboxane B2

• Catalog No.: D230555
• CAS Number: 67910-12-7
• M. F.: C20H32O6
• M. W.: 368.46448

SYNONYMS

• IUPAC name: (5Z)-7-[(2R,3S,4S)-4-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-6-oxooxan-3-yl]hept-5-enoic acid
• IUPAC Traditional name: 11-dehydro-thromboxane
• Synonyms: [2R-[2α(1E,3S*),3β(Z),4β]]-7-[Tetrahydro-4-hydroxy-2-(3-hydroxy-1-octenyl)-6-oxo-2H-pyran-3-yl] 5-Heptenoic Acid; 11-Dehydro-TXB2; (5Z)-7-[(2R,3S,4S)-Tetrahydro-4-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-6-oxo-2H-pyran-3-yl]-5-heptenoic Acid; (5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxo-thromboxa-5,13-dien-1-oic Acid; 11-keto-Thromboxane B2

DATABASE IDS

• CAS Number: 67910-12-7

DETAILS

Description (English)

A metabolite of Thromboxane that is an in vivo markers of oxidative stress and platelet activation. It is associated with adverse cardiovascular events in Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT).

REFERENCES

• Santilli, F. et al.: J. Am. Coll. Cardiol., 47, 391 (2006)
• Montine, T.J. et al.: PLoS One, 5, No pp given (2006)
• Boehm, E. et al.: J. Biol. Chem., 279, 7663 (2006)