Defluoro Aprepitant

• Catalog No.: D228990
• CAS Number: 170729-76-7
• M. F.: C23H22F6N4O3
• M. W.: 516.4361992

SYNONYMS

• IUPAC name: 3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholin-4-yl]methyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
• IUPAC Traditional name: 5-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholin-4-yl]methyl}-2,4-dihydro-1,2,4-triazol-3-one
• Synonyms: 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenyl-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one

DATABASE IDS

• CAS Number: 170729-76-7

DETAILS

Description (English)

NK-1 receptor antagonists for treating severe anxiety disorders. Antidepressant.

REFERENCES

• Culman, J., et al.: J. Physiol. Pharmacol., 73, 885 (1995)
• Teixeira, R., et al.: Eur. J. Pharm., 311, 7 (1995)