Deflazacort-d3 (Major)

• Catalog No.: D228977
• M. F.: C25H31NO6
• M. W.: 441.51674
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo(10,10,11-^2H₃)-5-oxa-7-azapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icosa-6,14,17-trien-8-yl]-2-oxoethyl acetate
• IUPAC Traditional name: 2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo(10,10,11-^2H₃)-5-oxa-7-azapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icosa-6,14,17-trien-8-yl]-2-oxoethyl acetate
• Synonyms: Azacort-d3; Dezacort-d3; L 5458-d3; Oxazacort-d3; Flantadin-d3; (11β,16β)-21-(Acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione-d3; Azacortinol-d3; Calcort-d3; DL 458IT-d3; Deflan-d3; Deflazacort-d3; Dezacor-d3; Lantadin-d3; MDL 458-d3

PROPERTIES

• Apperance: Pale Beige Solid
• Melting Point: 252-254°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Labelled Deflazacort (D228975). A systemic corticosteroid. A derivative of prednisolone. Used for rheumatoid arthritis and lupus.

REFERENCES

• Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967)
• Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1967)
• Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1967)
• Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1967)