Deferasirox-d4 (Mixture of 6-hydroxyphenyl-d4 isomers)

• Catalog No.: D228653
• M. F.: C42H30N6O8
• M. W.: 746.723

SYNONYMS

• IUPAC name: 4-{3-[2-hydroxy(^2H₄)phenyl]-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl}benzoic acid; 4-{5-[2-hydroxy(^2H₄)phenyl]-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl}benzoic acid
• IUPAC Traditional name: 4-{3-[2-hydroxy(^2H₄)phenyl]-5-(2-hydroxyphenyl)-1,2,4-triazol-1-yl}benzoic acid; 4-{5-[2-hydroxy(^2H₄)phenyl]-3-(2-hydroxyphenyl)-1,2,4-triazol-1-yl}benzoic acid
• Synonyms: 4-[5-(2-Hydroxyphenyl)-3-(6-hydroxyphenyl-2,3,4,5-d4)-1H-1,2,4-triazol-1-yl]benzoic Acid & 4-[3-(2-hydroxyphenyl)-5-(6-hydroxyphenyl-2,3,4,5-d4)-1H-1,2,4-triazol-1-yl]benzoic Acid (1:1)

PROPERTIES

• Apperance: Yellow Solid
• Solubility: Methanol

DETAILS

Description (English)

Labelled orally active tridentate iron chelator.

REFERENCES

• Hershko, C., et al.: Blood, 97, 1115 (2001)
• Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2001)
• Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2001)