Decladinose Roxithromycin (Roxithromycin Impurity B)

• Catalog No.: D226800
• CAS Number: 214902-82-6
• M. F.: C33H62N2O12
• M. W.: 678.85158
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-4,7,12,13-tetrahydroxy-3,5,7,9,11,13-hexamethyl-10-(2,4,7-trioxa-1-azaoctan-1-ylidene)-1-oxacyclotetradecan-2-one
• IUPAC Traditional name: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-4,7,12,13-tetrahydroxy-3,5,7,9,11,13-hexamethyl-10-(2,4,7-trioxa-1-azaoctan-1-ylidene)-1-oxacyclotetradecan-2-one
• Synonyms: Decladinoseroxithromycin; Roxithromycin Impurity B; (9E)-3-O-De(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)erythromycin 9-[O-[(2-Methoxyethoxy)methyl]oxime]; (9E)-3-O-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)erythromycin9-[O-[(2-Methoxyethoxy)methyl]oxime]

DATABASE IDS

• CAS Number: 214902-82-6

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 88-91°C
• Solubility: DMSO
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Roxithromycin impurity B. The inactive metabolite (M1) of Roxithromycin.

REFERENCES

• Ferrero, J., et al.: Drug Metab. Dispos., 18, 441 (1990)
• Gase, C., et al.: J. Antibiot., 44, 313 (1990)
• Markham, A., et al.: Drugs, 48, 297 (1990)
• Jarukamjorn, K., et al.: J. Pharm. Pharmacol., 50, 515 (1990)