N-Debenzoyl-3'-p-O-benzy-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl} Paclitaxel

• Catalog No.: D205135
• M. F.: C50H54Cl3NO16
• M. W.: 1031.31986
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-amino-3-[4-(benzyloxy)phenyl]-2-hydroxypropanoyl]oxy}-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-amino-3-[4-(benzyloxy)phenyl]-2-hydroxypropanoyl]oxy}-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate

PROPERTIES

• Apperance: Off-white Solid
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A protected Paclitaxel (Taxol) derivative. It can be useful for the treatment of cancer. Antitumor agent.

REFERENCES

• Xiao, X.-Y., et al.: J. Org. Chem., 62, 6029 (1997)