N-Debenzoyl-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl} Paclitaxel

• Catalog No.: D205125
• CAS Number: 114915-15-0
• M. F.: C43H48Cl3NO15
• M. W.: 925.19792

SYNONYMS

• IUPAC name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• Synonyms: N-Debenzoyl-7-[[(2,2,2-trichloroethoxy)carbonyl]oxy]taxol

DATABASE IDS

• CAS Number: 114915-15-0

PROPERTIES

• Apperance: White Solid
• Solubility: Ethyl Acetate
• Solubility: Methanol

DETAILS

Description (English)

A Paclitaxel (Taxol) derivative. It can be useful for the treatment of cancer. Antitumor agent.

REFERENCES

• Xiao, X.-Y., et al.: J. Org. Chem., 62, 6029 (1997)