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Deacetyl Vinorelbine_Molecular_structure_CAS_126347-74-8)
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Deacetyl Vinorelbine

Catalog No. D199010 Name Toronto Research Chemicals
CAS Number 126347-74-8 Website http://www.trc-canada.com
M. F. C43H52N4O7 Telephone +1 (416) 665-9696
M. W. 736.89558 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere Chembase ID: 165466

SYNONYMS

IUPAC name
methyl (1R,9R,10S,11R,12R,19R)-12-ethyl-4-[(12S,14R)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8,15-pentaen-12-yl]-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
IUPAC Traditional name
methyl (1R,9R,10S,11R,12R,19R)-12-ethyl-4-[(1R,12S,14R)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8,15-pentaen-12-yl]-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
Synonyms
O-Deacetylnavelbine
Desacetylnavelbine
O4-Deacetyl-3',4'-didehydro-4'-deoxy-C'-norvincaleukoblastine

DATABASE IDS

CAS Number 126347-74-8

PROPERTIES

Certificate of Analysis Download
Apperance Pale Yellow Solid
Melting Point >192°C (dec.)
Solubility Methanol
MSDS Link Download
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
A metabolite of Vinorelbine (V315000).

REFERENCES

  • Elmarakby, S., et al.: J. Med. Chem., 32, 2158 (1989)
  • Jehl, F., et al.: Cancer Res., 51, 2073 (1989)
  • Kajita, J., et al.: Drug Metab. Dispos., 28, 1121 (1989)
  • Puozzo, C., et al.: J. Pharm. Biomed. Anal., 44, 144 (1989)