Home > Compound List > Product Information
Dasatinib-d8 N-Oxide_Molecular_structure_CAS_1189988-36-0)
Click picture or here to close

Dasatinib-d8 N-Oxide

Catalog No. D193612 Name Toronto Research Chemicals
CAS Number 1189988-36-0 Website http://www.trc-canada.com
M. F. C22H26ClN7O3S Telephone +1 (416) 665-9696
M. W. 504.00494 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 165420

SYNONYMS

IUPAC name
4-[6-({5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}amino)-2-methylpyrimidin-4-yl]-1-(2-hydroxyethyl)(2H8)piperazin-1-ium-1-olate
IUPAC Traditional name
4-[6-({5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}amino)-2-methylpyrimidin-4-yl]-1-(2-hydroxyethyl)(2H8)piperazin-1-ium-1-olate
Synonyms
N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl-d8]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide N-Oxide

DATABASE IDS

CAS Number 1189988-36-0

PROPERTIES

Certificate of Analysis Download
Apperance Pale Yellow Solid
Melting Point >195°C (dec.)
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
The labelled oxidative metabolite of Dasatinib (M5 metabolite).

REFERENCES

  • Cashman, J.R., et al.: Chem. Res. Toxicol., 8, 165 (1995)
  • Aasmoe, L., et al.: Toxicol. Appl. Pharmacol., 150, 86 (1995)
  • Galetin, A., et al.: J. Pharmacol. Exp. Ther., 314, 180 (1995)
  • Christopher, L.J., et al.: Drug Metab. Dispos., 36, 1357 (1995)