Dasatinib N-Oxide

• Catalog No.: D193610
• CAS Number: 910297-52-8
• M. F.: C22H26ClN7O3S
• M. W.: 504.00494
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 4-[6-({5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}amino)-2-methylpyrimidin-4-yl]-1-(2-hydroxyethyl)piperazin-1-ium-1-olate
• IUPAC Traditional name: 4-[6-({5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}amino)-2-methylpyrimidin-4-yl]-1-(2-hydroxyethyl)piperazin-1-ium-1-olate
• Synonyms: N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide N-Oxide

DATABASE IDS

• CAS Number: 910297-52-8

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 193-195°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

An oxidative metabolite of Dasatinib (M5 metabolite).

REFERENCES

• Cashman, J.R., et al.: Chem. Res. Toxicol., 8, 165 (1995)
• Aasmoe, L., et al.: Toxicol. Appl. Pharmacol., 150, 86 (1995)
• Galetin, A., et al.: J. Pharmacol. Exp. Ther., 314, 180 (1995)
• Christopher, L.J., et al.: Drug Metab. Dispos., 36, 1357 (1995)