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Dasatinib-d8
Catalog No.	D193602	Name	Toronto Research Chemicals
CAS Number		Website	http://www.trc-canada.com
M. F.	C22H26ClN7O2S	Telephone	+1 (416) 665-9696
M. W.	488.00554	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage	-20°C Freezer	Chembase ID: 165417

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SYNONYMS

IUPAC name

N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)(²H₈)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide

IUPAC Traditional name

N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)(²H₈)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide

Synonyms

BMS-354825-d8

N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl-d8]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide

DATABASE IDS

PROPERTIES

Certificate of Analysis	Download
Apperance	Off-White to Light Tan Solid
Melting Point	259-262°C
Solubility	Dimethyl Sulfoxide
Solubility	Methanol
MSDS Link	Download
Storage Condition	-20°C Freezer

DETAILS

Description (English)

A new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic.

REFERENCES

Lombardo, L.J., et al: J. Med. Chem., 47, 6658 (2004)
Shah, N. P., et al.: Science, 305, 399 (2004)
O’Hare, T., et al.: Curr. Opin. Genet. Dev., 16, 92 (2004)