Darunavir O-β-D-Glucuronide

• Catalog No.: D193515
• CAS Number: 1159613-27-0
• M. F.: C33H45N3O13S
• M. W.: 723.7877

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6R)-6-{[(2R,3S)-3-({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl}amino)-1-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-4-phenylbutan-2-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6R)-6-{[(2R,3S)-3-({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl}amino)-1-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-4-phenylbutan-2-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: (1R,2S)-1-[[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]methyl]-2-[[[[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]amino]-3-phenylpropyl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 1159613-27-0

DETAILS

Description (English)

A metabolite of Darunavir (D193500); an inhibitor of human immunodeficiency virus protease.

REFERENCES

• Vermeir, M. et al.: Drug Metab. Disp., 37, 809 (2009)
• Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2009)
• Arasteh, K., et al.: AIDS, 19, 943 (2009)