Darunavir N-β-D-Glucuronide

• Catalog No.: D193510
• CAS Number: 1159613-25-8
• M. F.: C33H45N3O13S
• M. W.: 723.7877

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6R)-6-[(4-{[(2R,3S)-3-({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl}amino)-2-hydroxy-4-phenylbutyl](2-methylpropyl)sulfamoyl}phenyl)amino]-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6R)-6-[(4-{[(2R,3S)-3-({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl}amino)-2-hydroxy-4-phenylbutyl](2-methylpropyl)sulfamoyl}phenyl)amino]-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: 1-Deoxy-1-[[4-[[[(2R,3S)-3-[[[[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]amino]-2-hydroxy-4-phenylbutyl](2-methylpropyl)amino]sulfonyl]phenyl]amino]-β-D-glucopyranuronic Acid

DATABASE IDS

• CAS Number: 1159613-25-8

DETAILS

Description (English)

A metabolite of Darunavir (D193500); an inhibitor of human immunodeficiency virus protease.

REFERENCES

• Vermeir, M. et al.: Drug Metab. Disp., 37, 809 (2009)
• Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2009)
• Arasteh, K., et al.: AIDS, 19, 943 (2009)