Dabigatran Etexilate Mesylate

• Catalog No.: D100150
• CAS Number: 872728-81-9
• M. F.: C35H45N7O8S
• M. W.: 723.8389
• Storage: Refrigerator

SYNONYMS

• IUPAC name: methanesulfonic acid ethyl 3-{1-[2-({[4-({[(hexyloxy)carbonyl]amino}methanimidoyl)phenyl]amino}methyl)-1-methyl-1H-1,3-benzodiazol-5-yl]-N-(pyridin-2-yl)formamido}propanoate
• IUPAC Traditional name: methanesulfonic acid ethyl 3-{1-[2-({[4-({[(hexyloxy)carbonyl]amino}methanimidoyl)phenyl]amino}methyl)-1-methyl-1,3-benzodiazol-5-yl]-N-(pyridin-2-yl)formamido}propanoate
• Synonyms: BIBR 1048MS; Pradaxa; N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine Ethyl Ester Methanesulfonate

DATABASE IDS

• CAS Number: 872728-81-9

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >132°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Nonpeptide, direct thrombin inhibitor. Antithrombotic.

REFERENCES

• Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002)
• Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002)
• Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2002)